Gastric Motor and Sensory Functions in Obesity
نویسندگان
چکیده
منابع مشابه
Role of nitric oxide in gastric motor and sensory functions in healthy subjects.
BACKGROUND AND AIMS Impaired accommodation and hypersensitivity to distension of the proximal stomach are considered to be important factors in the pathogenesis of dyspeptic complaints. As fundus relaxing agents may be effective in the treatment of these symptoms, insight into the mediators involved in fundic accommodation and associated perceptual responses is important. Therefore, we studied ...
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BACKGROUND Pharmacological approaches to alter satiation may have an impact on functional upper gastrointestinal disorders and potentially change food intake in obesity. AIM Our aim was to compare the effects of two doses of octreotide and placebo on postprandial symptoms, gastric accommodation, and gastric emptying using validated non-invasive techniques. METHODS In a randomised, parallel ...
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AIMS/INTRODUCTION Gastric inhibitory polypeptide (GIP) is an incretin secreted from the gastrointestinal tract after an ingestion of nutrients, and stimulates an insulin secretion from the pancreatic islets. Additionally, GIP has important roles in extrapancreatic tissues: fat accumulation in adipose tissue, neuroprotective effects in the central nervous system and an inhibition of bone resorpt...
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Prior studies have demonstrated that inflammation can sensitize visceral afferent neurons, contributing to the development of hyperalgesia. We hypothesized that both afferent and efferent pathways are affected, resulting in changes in motor and sensory function. Kissing ulcers (KU) were induced in the distal stomach by injecting 60% acetic acid for 45 s into a clamped area of the stomach. In co...
متن کاملMOTILITY AND VISCERAL SENSATION Role of nitric oxide in gastric motor and sensory functions in healthy subjects
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ژورنال
عنوان ژورنال: Obesity Research
سال: 2005
ISSN: 1071-7323
DOI: 10.1038/oby.2005.51